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epidermal growth factor receptor egfr protein  (MedChemExpress)


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    MedChemExpress epidermal growth factor receptor egfr protein
    Epidermal Growth Factor Receptor Egfr Protein, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/epidermal growth factor receptor egfr protein/product/MedChemExpress
    Average 94 stars, based on 2 article reviews
    epidermal growth factor receptor egfr protein - by Bioz Stars, 2026-02
    94/100 stars

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    Worse prognosis of non-responders in arm Cam+TPF (A) Spatial heatmaps showing expression intensity of EGFR , including Cam+TPF-pNR group ( n = 2) and Cam-pNR group ( n = 2); scale bar, 5 mm. (B) Dot plot showing expression levels of genes related to EGFR signaling pathway, including Cam+TPF-pNR group ( n = 2) and Cam-pNR group ( n = 2). (C) Heatmap showing the quantitative immunohistochemical results of post-therapy EGFR and downstream proteins in non-responders in arm Cam+TPF compared with arm Cam, including Cam+TPF-pNR group ( n = 2) and Cam-pNR group ( n = 7). (D) Follow-up of the two non-responders in arm Cam+TPF. Red circle indicates primary tumor, red arrow indicates tumor metastasis. EGFR, epidermal growth factor receptor; CT, computed tomography; MRI, magnetic resonance imaging; PET-CT, positron emission tomography and computed tomography.

    Journal: Cell Reports Medicine

    Article Title: Neoadjuvant immunotherapy with or without chemotherapy in locally advanced oral squamous cell carcinoma: Randomized, two-arm, phase 2 trial

    doi: 10.1016/j.xcrm.2025.101930

    Figure Lengend Snippet: Worse prognosis of non-responders in arm Cam+TPF (A) Spatial heatmaps showing expression intensity of EGFR , including Cam+TPF-pNR group ( n = 2) and Cam-pNR group ( n = 2); scale bar, 5 mm. (B) Dot plot showing expression levels of genes related to EGFR signaling pathway, including Cam+TPF-pNR group ( n = 2) and Cam-pNR group ( n = 2). (C) Heatmap showing the quantitative immunohistochemical results of post-therapy EGFR and downstream proteins in non-responders in arm Cam+TPF compared with arm Cam, including Cam+TPF-pNR group ( n = 2) and Cam-pNR group ( n = 7). (D) Follow-up of the two non-responders in arm Cam+TPF. Red circle indicates primary tumor, red arrow indicates tumor metastasis. EGFR, epidermal growth factor receptor; CT, computed tomography; MRI, magnetic resonance imaging; PET-CT, positron emission tomography and computed tomography.

    Article Snippet: Tumor biopsy and surgical samples were collected and examined for a panel of checkpoint molecules, immunocyte subsets and epidermal growth factor receptor (EGFR) signaling proteins using immunohistochemistry, including EGFR (CST, D38B1, 4267S, 1:400), p -EGFR (Tyr1068) (CST, 2234S, 1:200), p -p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (CST, D13.14.4E, 4370S, 1:200), p -p38 MAPK (Thr180/Tyr182) (CST, D3F9, 4511S, 1:200), p -Akt (Ser473) (CST, D9E, 4060S, 1:200), CD3ε (CST, D7A6E, 85061S, 1:200), CD4 (Abcam, ab133616, 1:400), CD8α (CST, D8A8Y, 85336S, 1:400), CD14 (Abcam, ab182032, 1:400), CD68 (CST, D4B9C, 76437S, 1:400), CD11b (CST, D6X1N, 49420S, 1:200), CD11c (Abcam, ab52632, 1:200), CD20 (Abcam, ab64088, 1:200), Foxp3 (CST, D2W8E, 98377S, 1:100), CD56 (CST, 123C3, 3576S, 1:100), TIM-3 (CST, D5D5R, 45208S, 1:50), TIGIT (Abcam, ab243903, 1:200), PD-1 (CST, EH33, 43248S, 1:100).

    Techniques: Expressing, Immunohistochemical staining, Computed Tomography, Magnetic Resonance Imaging, Positron Emission Tomography-Computed Tomography, Positron Emission Tomography